RK20590

E. coli SSB (single-stranded binding) protein is a single-stranded DNA (ssDNA) binding protein essential for E. coli DNA replication and repair. The tetramer formed by the SSB protein specifically binds 8-16 nucleotides, thereby protecting ssDNA from nuclease degradation. In vitro experiments have shown that this protein can stabilize single-stranded regions of DNA, thereby relaxing double-stranded regions, which enhances the activity of DNA polymerase.

E. coli SSB (single-stranded binding) protein is a single-stranded DNA (ssDNA) binding protein essential for E. coli DNA replication and repair. The tetramer formed by the SSB protein specifically binds 8-16 nucleotides, thereby protecting ssDNA from nuclease degradation. In vitro experiments have shown that this protein can stabilize single-stranded regions of DNA, thereby relaxing double-stranded regions, which enhances the activity of DNA polymerase.