Z03699-0.1

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GenCRISPR™ SaCas9 2NLS Nuclease
The GenCRISPR™
SaCas9 2NLS Nuclease can be formed with the guide RNA into a ribonucleoprotien
(RNP) complex. The use of an RNP complex to perform gene editing has been shown
to reduce the challenges encountered with other CRISPR gene editing techniques
such as viral and plasmid delivery. Challenges include off-target effects, cell
viability and transcription/translational challenges. The SaCas9 recognizes an
NNGRRT protospacer adjacent motif (PAM) and cleaves target DNA at high
efficiency with a variety of guide RNA (gRNA) spacer lengths.
GenCRISPR™ SaCas9 2NLS
Nuclease is a tag free nuclease produced by expression in an E. coli strain carrying a plasmid
encoding the Cas9 gene from Staphylococcus
aureus with a nuclear localization signal at both N-terminal and C-terminal.The
small size of the nuclease facilitates enhanced in vivo delivery for genome
editing in various organisms.
$162.15 Add to cart View Product Details

Adva Tech Group, Inc. is a distributor of Life Science Reagents and Chemicals. Our customer base includes industries such as Advanced Technologies, Biologicals, Clinical, Controlled Environments and Cleanroom Solutions, Education, Environmental, Federal Government, Forensics, Food and Beverage, Industrial, Molecular Diagnostics, Petrochemical, Pharmaceuticals and Biotechnology, State and Local Government.

As a newly established supplier of chemicals and equipment, we offer a comprehensive supply of chemistry & laboratory equipment, designed to meet the rigorous demands of your research, experiments, and manufacturing needs. Our inventory offers everything from basic to advanced chemicals and equipment, ensuring that whether you are conducting complex chemical manufacturing or routine testing, you have access to top-quality chemistry & lab supplies.