Uncategorized

4-[(tert-Butoxycarbonylamino)methyl]benzoic Acid

4-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzoic Acid

4-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzoic Acid

4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline

4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline

4-1BB(CD137) is a member of the tumor necrosis factor (TNF) receptor family. Mature human 4-1BB consists of a 163 amino acid extracellular domain (ECD) with four TNFR cysteine‑rich repeats, a 27 aa transmembrane segment, and a 42 aa cytoplasmic domain; 4-1BB (CD137) is expressed as a disulfide-linked homodimer on various populations of activated T cell including CD4+, CD8+, memory CD8+, NKT, and regulatory T cells as well as on myeloid and mast cell progenitors, dendritic cells, mast cells, and bacterially infected osteoblasts. It binds with high affinity to the transmembrane 4-1BB Ligand/TNFSF9 which is expressed on antigen presenting cells and myeloid progenitor cells. This interaction co stimulates the proliferation, activation, and/or survival of the 4-1BB expressing cell. It can also enhance the activation-induced cell death of repetitively stimulated T cells.

4-1BB(CD137) is a member of the tumor necrosis factor (TNF) receptor family. Mature human 4-1BB consists of a 163 amino acid extracellular domain (ECD) with four TNFR cysteine‑rich repeats, a 27 aa transmembrane segment, and a 42 aa cytoplasmic domain; 4-1BB (CD137) is expressed as a disulfide-linked homodimer on various populations of activated T cell including CD4+, CD8+, memory CD8+, NKT, and regulatory T cells as well as on myeloid and mast cell progenitors, dendritic cells, mast cells, and bacterially infected osteoblasts. It binds with high affinity to the transmembrane 4-1BB Ligand/TNFSF9 which is expressed on antigen presenting cells and myeloid progenitor cells. This interaction co stimulates the proliferation, activation, and/or survival of the 4-1BB expressing cell. It can also enhance the activation-induced cell death of repetitively stimulated T cells.

Monoclonal Antibodies

Monoclonal Antibodies

Polyclonal Antibodies

Polyclonal Antibodies

Monoclonal Antibodies

Monoclonal Antibodies

Tumor necrosis factor ligand superfamily member 9(4-1BBL) is single-pass type II membrane protein which is a member of the the tumor necrosis factor family. 4 1BBL is a 254 amino acids cytokine that is expressed in brain, placenta, lung, skeletal muscle and kidney. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine may have a role in activation-induced cell death (AICD) and cognate interactions between T-cells and B-cells/macrophages. It has also been shown to be required for the optimal CD8 responses in CD8 T cells, and is thought to be involved in T cell-tumor cell interaction.

Tumor necrosis factor ligand superfamily member 9(4-1BBL) is single-pass type II membrane protein which is a member of the the tumor necrosis factor family. 4 1BBL is a 254 amino acids cytokine that is expressed in brain, placenta, lung, skeletal muscle and kidney. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine may have a role in activation-induced cell death (AICD) and cognate interactions between T-cells and B-cells/macrophages. It has also been shown to be required for the optimal CD8 responses in CD8 T cells, and is thought to be involved in T cell-tumor cell interaction.

4-Acetamidobenzenesulfonamide

4-Acetamidobenzenesulfonyl Azide

4-Acetamidobenzenesulfonyl Azide

4-Acetamidobenzenesulfonyl Azide

4-Acetamidobenzenesulfonyl Chloride

4-Acetoxybenzaldehyde

4-Acetoxybenzaldehyde

4-Amino-2-chloropyridine

4-Amino-2-chloropyridine

4-Amino-2-chloropyridine

4-Amino-2-methyl-5-pyrimidinemethanol

4-Amino-2-methyl-5-pyrimidinemethanol

4-Amino-3-hydrazino-5-mercapto-1,2,4-triazole, [for Determination of Aldehydes]

4-Amino-3-hydrazino-5-mercapto-1,2,4-triazole, [for Determination of Aldehydes]

4-Amino-3-hydroxy-1-naphthalene Sulfonic Acid, Reagent, ACS

4-Amino-3-hydroxy-1-naphthalene Sulfonic Acid, Reagent, ACS

4-Amino-3-hydroxy-1-naphthalene Sulfonic Acid, Reagent, ACS

4-Amino-3-hydroxy-1-naphthalene Sulfonic Acid, Reagent, ACS

4-Amino-3-hydroxy-1-naphthalene Sulfonic Acid, Reagent, ACS

4-Amino-3,5-xylenol

4-Amino-5-Imidazolecarboxamide, 98+ Percent

4-Amino-5-Imidazolecarboxamide, 98+ Percent

4-Aminoantipyrine

4-Aminoantipyrine

4-Aminoantipyrine

4-Aminoantipyrine

4-Aminoazobenzene

4-Aminoazobenzene

4-Aminobenzamidine Dihydrochloride

4-Aminobenzamidine Dihydrochloride

4-Aminobenzamidine Dihydrochloride

4-Aminobenzoic Acid

4-Aminobenzoic Acid