10g

Platelet-Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle, connective tissue, bone and cartilage cells, and some blood cells. The PDGF is involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. The PDGF family consists of proteins derived from four genes (PDGF -A, -B, -C, and -D) that form four disulfide-linked homodimers (PDGF-AA, -BB, -CC, and -DD) and one heterodimer (PDGF-AB).

PDGF-DD, also known as platelet-derived growth factor D, IEGF and SCDGFB, is asecreted growth factor belonging to the PDGF/VEGFfamily. It is highly expressed in the heart, pancreas, adrenal glands and ovary. PDGF-DD forms functional homodimers that bind and induce PDGF Rβ homodimers and PDGF Rα/β heterodimers that promote intracellular signaling. This plays an important role in the regulation of cell differentiation, migration and survival. It has also been reported that PDGF-DD can induce monocyte and macrophage recruitment, increase interstitial pressure and facilitate wound healing.

Molecular Formula : No Data Available

Molecular Formula : (C2H4O)nC12H24O2

Molecular Formula : C19 H21 Cl N2 O

Molecular Formula : C6 Cl5 O . Na

Molecular Formula : C7 H3 Cl5 S

Molecular Formula : C15 H30 O2

Molecular Formula : C15 H28 O2

Molecular Formula : C17H20O8

Molecular Formula : C14H18O7

Molecular Formula : C7HF5O2

Molecular Formula : C7 Cl F5 O

Pentafluorophenol

Molecular Formula : C10H10N2P2S5

Molecular Formula : C13 H18 N4 O3

Molecular Formula : C6 H10 N4

Molecular Formula : Cl H O4

Molecular Formula : C5 F12

Molecular Formula : C7F14O4S

Molecular Formula : C7 H F13 O2

Molecular Formula : C7F15I

Molecular Formula : C6 H F11 O2

Molecular Formula : C8 H4 F13 I

Molecular Formula : C12 F27 N

Molecular Formula : C8 H10 Cl2 O2

Molecular Formula : C20 H12

Platelet factor 4, also known as CXCL4, is expressed in megakaryocytes and stored in the α-granules of platelets. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines. Platelet factor 4 can be antiproliferative and antiangiogenic, at least in part via interfering with FGF2 and VEGF heparin binding and thus inhibiting their signaling. However, it can also be proinflammatory and proatherogenic through multiple effects on monocytes, macrophages and endothelial cells.

Molecular Formula : C12 H8 N2

Molecular Formula : C8 H10 O

Molecular Formula : C9H9NO

Molecular Formula : C10 H15 N5 . Cl H

Molecular Formula : C10 H13 N O2 . Cl H

Molecular Formula : C9H10N2O

Molecular Formula : C23 H26 O3

Molecular Formula : C9H10O2

Molecular Formula : C18 H22 Cl N O . Cl H

Molecular Formula : C10 H13 N O2

Molecular Formula : C12 H17 O4 P S2

Molecular Formula : C13 H10 O3

Molecular Formula : C7H5ClOS

Molecular Formula : C20H24O10

Molecular Formula : C8H11ClSi

Molecular Formula : C8 H6 O3

Molecular Formula : C6 H8 N2 . Cl H

Molecular Formula : C16H21NO5

Molecular Formula : C7H7FO2S

Molecular Formula : C6H5Cl2OP