1mg

Molecular Formula : C20H13NO7

Molecular Formula : C5 13C H12 O5

Molecular Formula : C21H14O7

Molecular Formula : C16H22N6O3S

Molecular Formula : C25 D7 H35 O3

Molecular Formula : C18H16D6O6

Molecular Formula : C13H14N8O2

Molecular Formula : C14H16O9

Molecular Formula : C213C6H8O3

Molecular Formula : CH6O7P2 . x(Na)

Molecular Formula : C41H39D4NO13S

Molecular Formula : C19 H30 O2

Molecular Formula : C12H10D3N

Molecular Formula : C5 D3 H8 Na2 O7 P

Molecular Formula : C19 H26 O2

Molecular Formula : C39H42Cl2F2N2O6

Molecular Formula : C12H16N2O4

Molecular Formula : C11 2H3 H10 N O3 . Cl H

Molecular Formula : C14H10D10ClNO2

Molecular Formula : C15H16D6NNaO5S

Molecular Formula : C15H10D11NO4

Molecular Formula : C15H11D11ClNO2

Molecular Formula : C16H9D7ClN3O3S

Molecular Formula : C21 H26 N4 O3

Molecular Formula : C22H21D6N3O3S2

Molecular Formula : C14H16D5NO4

Molecular Formula : C15 D7 H18 N O3 . Cl H

Molecular Formula : C24 H32 N2 O5

Molecular Formula : No Data Available

Molecular Formula : C19 H24 O2

Molecular Formula : C12 H17 N3 O9

Molecular Formula : C6 2H4 H5 N3 O3

Molecular Formula : C11H12D6ClNO

Molecular Formula : C24 H32 O5

Molecular Formula : C26H41N3O5

Molecular Formula : C20 H30 O2

Molecular Formula : C20H27D3O2

Molecular Formula : C18H9D5Cl4N2O • HNO3

Molecular Formula : C18 H13 Cl F N3 O

Molecular Formula : C18H7D6ClFN3O2

Molecular Formula : C22 H22 Cl N3 O3

Molecular Formula : C18D6H7ClFN3

Molecular Formula : C35 H30 N4 O4

Macrophage Migration Inhibitory Factor (MIF) is a pleiotropic cytokine, existing as a homotrimer in vivo. MIF was originally identified as a T cell derived factor responsible for the inhibition of macrophage migration. However, recently MIF has received much more attention because of its possible roles in angiogenesis and cancer development. MIF is over-expressed in various cancers, including pancreatic, breast, colon, brain, prostate, skin, and lung. The intratumoral expression of MIF is strongly correlated with angiogenic growth factor expression, such as the expression of Interleukin 8 (IL-8) and Vascular Endothelial Growth Factor (VEGF), and with risk of recurrence after resection.

Macrophage migration inhibitory factor (MIF or MMIF), also named as glycosylation-inhibiting factor (GIF), L-dopachrome isomerase, or phenylpyruvate tautomerase, is a protein encoded by the MIF gene. It is released from white blood cells by bacterial antigen stimulation to trigger an acute immune response, or by glucocorticoids to counter-act the inhibitory effects of glucocorticoids on immune system. MIF is a homotrimer of which each subunit contains 115 amino acids. As mentioned above, MIF is involved in the innate immune response to bacterial pathogens and counter-acts the anti-inflammatory activity of glucocorticoids. Furthermore, it also plays a role as mediator in regulating the function of macrophages in host defense and has phenylpyruvate tautomerase and dopachrome tautomerase activity in vitro. Mouse MIF is active on human cells, while human MIF is active on mouse cells. Mouse MIF is 99 %, 84 %, 90 %, and 90 % a.a. identical to rat, porcine, bovine and human MIF, respectively.

Molecular Formula : C29 D3 H32 N O2

Chemokine (C-X-C motif) ligand 9 (CXCL9), also known as monokine induced by interferon gamma (MIG), is a small cytokine belonging to the CXC chemokine family. The CXCL9 gene is induced in macrophages and in primary glial cells of the central nervous system specifically in response to IFNγ. CXCL9 has been shown to be a chemoattractant for activated T-lymphocytes and TIL but not for neutrophils or monocytes. The human CXCL9 cDNA encodes a 125 amino acid residue precursor protein with a 22 amino acid residue signal peptide that is cleaved to yield a 103 amino acid residue mature protein. CXCL9 has an extended carboxy-terminus containing greater than 50% basic amino acid residues and is larger than most other chemokines. A chemokine receptor (CXCR3) specific for CXCL9 and IP-10 has recently been cloned and shown to be highly expressed in IL-2-activated T-lymphocytes.

Chemokine (C-X-C motif) ligand 9 (CXCL9), also known as monokine induced by interferon gamma (MIG), is a small cytokine belonging to the CXC chemokine family.The CXCL9 gene is induced in macrophages and in primary glialcells of the central nervous systemin response to IFN­γ. CXCL9 has been shown to be achemo attractant for activated Th1lymphocytes and tumor-infiltrating leukocytes (TILs) but not for neutrophils or monocytes. CXCL is also involved in other cellular activities including inhibition of tumor growth, angiogenesis, and inhibition of colony formation of hematopoietic progenitors. CXCL9 is closely related to two other CXC chemokines, CXCL10 and CXCL11.CXCL9, CXCL10 and CXCL11 all elicit their chemotactic functions by interacting with the chemokine receptor CXCR3.

Molecular Formula : C6H11D3N2O2