1mg
Showing 7201–7250 of 7911 results
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Sebacyl-CoA Sodium Salt
Molecular Formula : C31H52N7O19P3S • xNa
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Sebuthylazine-d5 (ethyl-d5)
Molecular Formula : C9 2H5 H11 Cl N5
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Secalciferol
Molecular Formula : C27 H44 O3
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Secalciferol-d6
Molecular Formula : C27 2H6 H38 O3
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seco Everolimus B (~90%)
Molecular Formula : C53H85NO15
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Secorapamycin B
Molecular Formula : C51H81NO14
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Selexipag D-Mannitol Ester (>80%)
Molecular Formula : C31H41N3O8
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Semagacestat
Molecular Formula : C19 H27 N3 O4
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Semicarbazide-13C,15N2 Hydrochloride
Molecular Formula : 13C H5 15N2 N O . Cl H
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Senecionine N-Oxide-D3
Molecular Formula : C18H22D3NO6
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Sermorelin Acetate
Molecular Formula : C149H246N44O42S • xC2H4O2
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Serotonin-d4 Beta-D-Glucuronide
Molecular Formula : C16H16D4N2O7
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Sertindole-d4
Molecular Formula : C24H22D4ClFN4O
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Sertraline Carbamoyl Glucuronide
Molecular Formula : C24 H25 Cl2 N O8
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Sertraline-13C, 15N, d3 Hydrochloride
Molecular Formula : 13C C16 D3 H14 Cl2 15N . H Cl
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Sertraline-d3 Hydrochloride
Molecular Formula : C17 2H3 H14 Cl2 N . Cl H
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Sertraline-RC 11 Impurity Hydrochloride
Molecular Formula : C17H17Cl2N • HCl
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Sesamin
Molecular Formula : C20 H18 O6
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Setiptiline-d3
Molecular Formula : C19H16D3N
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SGI-1027
Molecular Formula : C27 H23 N7 O
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Shanzhiside Methyl Ester
Molecular Formula : C17 H26 O11
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Shh (C24II), Human
Sonic Hedgehog (Shh) is a member of the Hedgehog (Hh) family of highly conserved proteins which are widely represented throughout the animal kingdom. In mammal, there are three related Hh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh). They share a high degree of amino-acid sequence identity (e.g., Shh and Ihh are 93% identical). Sonic Hedgehog plays a role in cell growth, cell specialization, and the normal shaping (patterning) of the body. Shh is also important for development of the brain and spinal cord (central nervous system), eyes, limbs, and many other parts of the body.
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Shh (C25II), Mouse
Sonic Hedgehog (Shh) is a member of the Hedgehog (Hh) family of highly conserved proteins which are widely represented throughout the animal kingdom. In mammal, there are three related Hh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh). They share a high degree of amino-acid sequence identity (e.g., Shh and Ihh are 93% identical). Sonic Hedgehog plays a role in cell growth, cell specialization, and the normal shaping (patterning) of the body. Shh is also important for development of the brain and spinal cord (central nervous system), eyes, limbs, and many other parts of the body.
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Shh, Human
Members of the Hedgehog (Hh) family are highly conserved proteins which are widely represented throughout the animal kingdom. The three known mammalian Hh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh) are structurally related and share a high degree of amino-acid sequence identity (e.g., Shh and Ihh are 93% identical). The biologically active form of Hh molecules is obtained by autocatalytic cleavage of their precursor proteins and corresponds to approximately the N-terminal one half of the precursor molecule. Although Hh proteins have unique expression patterns and distinct biological roles within their respective regions of secretion, they use the same signaling pathway and can substitute for each other in experimental systems.
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Shh, Mouse
Members of the Hedgehog (Hh) family are highly conserved proteins which are widely represented throughout the animal kingdom. The three known mammalian Hh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh) are structurally related and share a high degree of amino-acid sequence identity (e.g., Shh and Ihh are 93% identical). The biologically active form of Hh molecules is obtained by autocatalytic cleavage of their precursor proteins and corresponds to approximately the N-terminal one half of the precursor molecule. Although Hh proteins have unique expression patterns and distinct biological roles within their respective regions of secretion, they use the same signaling pathway and can substitute for each other in experimental systems.
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Shikimate-3-phosphate Trisodium Salt (90%)
Molecular Formula : C7 H8 O8 P . 3 Na
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Siglec-10 Fc Chimera, Human
Siglec-10 is immune system-restricted and highly expressed in peripheral blood leukocytes. Siglec-10 preferably binds to α-2,3- or α-2,6-linked sialic acid (similarity). Siglec10 is involved in the negative regulation of B cell antigen receptor signal transduction. The inhibition of B cell activation depends on PTPN6/SHP-1 (by similarity). The binding of Siglec10 to CD24 may be involved in the selective suppression of the immune response (by similarity) to risk-related molecular patterns (DAMPs) (such as HMGB1, HSP70 and HSP90). The combination of Siglec10 and CD24 may regulate the immune response of natural killer (NK) cells. Play a role in controlling autoimmunity (by similarity). In the process of initiating an adaptive immune response by CD8-α+ dendritic cells, cross-presentation is inhibited by weakening the formation of MHC class I peptide complexes. The function seems to imply the recruitment of PTPN6/SHP-1, which dephosphorylates NCF1 of the NADPH oxidase complex, thereby promoting phagosome acidification (by similarity).
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Siglec-15 Fc Chimera, Human
Siglec-15 preferentially recognizes the Neu5Acalpha2-6GalNAcalpha- structure. Siglec-15 associates with the activating adaptor proteins DNAX activation protein (DAP)12 and DAP10 via its lysine residue in the transmembrane domain. Siglec-15 is the second human Siglec identified to have an activating signaling potential; unlike Siglec-14, however, it does not have an inhibitory counterpart.
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sIL-6Rα, His, Human
Interleukin-6 Receptor (IL-6R) is a single trans-membrane protein that is the receptor for Interleukin-6 (IL-6). IL-6R forms a hexameric complex upon binding 2 molecules of IL-6 and two molecules of glycoprotein 130 (gp130) which activates intracellular JAK/STAT pathways. Although the normal form of IL-6R is the membrane-bound 80 kDa subunit, a soluble form of IL-6R (sIL-6R) can be generated physiologically by limited proteolysis or alternative splicing. sIL-6R binds to both IL-6 and gp130 generating intracellular signaling. In the immune system, sIL-6R is produced by both naïve and memory CD4 T-cells and strongly augments IL-6 ligand’s induction of Th-17 cells.
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Sildenafil Citrate-d3
Molecular Formula : C22H27D3N6O4S • (C6H8O7)
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Sildenafil-d3
Molecular Formula : C22 D3 H27 N6 O4 S
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Sildenafil-d8
Molecular Formula : C22 2H8 H22 N6 O4 S
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Silodosin b-D-Glucuronide Sodium Salt (>90%)
Molecular Formula : C31H39F3N3NaO10
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Silodosin Beta-D-Glucuronide N-Carboxybenzyl O-Methyl Tri-acetate
Molecular Formula : C46H54F3N3O15
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Silybin A
Molecular Formula : C25 H22 O10
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Silybin A+B mixture – D3
Molecular Formula : C25 D3 H19 O10
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Silybin B
Molecular Formula : C25 H22 O10
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Simvastatin Dimer
Molecular Formula : C50 H76 O10
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Simvastatin Hydroxy Acid Sodium Salt
Molecular Formula : C25 H39 O6 . Na
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Simvastatin t-Butyldimethylsilyl Acyl-Beta-D-glucuronide-O-acrylate
Molecular Formula : C46H80O12Si2
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Simvastatin-d6
Molecular Formula : C25H32D6O5
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Simvastatin-d6 Hydroxy Acid Ammonium Salt
Molecular Formula : C25H37D6NO6
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Simvastatin-d6 Hydroxy Acid Sodium Salt
Molecular Formula : C25H33D6NaO6
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Sinapic Acid Acyl-beta-D-glucoside
Molecular Formula : C17H22O10
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SIRPα Fc Chimera, Human
Signal regulatory protein alpha (SIRPα, designated CD172a), is also known as CD172 antigen-like family member A (CD172a), also called SHPS-1 (SHP substrate 1) and previously, MyD-1 (Myeloid/Dendritic-1), which is a monomeric about 90kDa type I transmembrane glycoprotein that belongs to the SIRP/SHPS (CD172) family of the immunoglobulin superfamily. SIRPα is Ubiquitous and highly expressed in brain. SIRPA/CD172a is immunoglobulin-like cell surface receptor for CD47 and acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. SIRPA/SHPS-1 supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment and may play a key role in intracellular signaling during synaptogenesis and in synaptic function by similarity. SIRPα recognition of surfactants SP-A and SP-D in the lung can inhibit alveolar macrophage cytokine production.
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Sitagliptin Carbamoyl Beta-D-Glucuronide Sodium Salt
Molecular Formula : C23H22F6N5NaO9
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Sitagliptin N-Sulfate Sodium Salt
Molecular Formula : C16H15F6NaN5O4S
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Sitagliptin-d4 Phosphate
Molecular Formula : C16 2H4 H11 F6 N5 O . H3 O4 P
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Skepinone-L
Molecular Formula : C24 H21 F2 N O4
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SkQR1
Molecular Formula : C44H56N2O6