1mg

Molecular Formula : C36H51BF2N2O

Molecular Formula : C25 H40 N2 O14 S

Molecular Formula : 13C6 C6 H21 N O8 S

Molecular Formula : C12 2H12 H9 N O8 S

Molecular Formula : C23 2H6 H17 N3 O5

Molecular Formula : C23 D6 H18 N3 Na O6

Molecular Formula : C16 2H7 H13 N4 O3 S

Molecular Formula : C12 H10 F N3 O2 S

Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.

Thrombopoietin (TPO), also known as C-mpl ligand, MGDF and Thpo, is a glycoprotein hormone belonging to the EPO/TPO family. It is expressed mainly in the liver, kidney and skeletal muscle. TPO binds and signals through MLP/C_MPL receptor. It stimulates the proliferation and maturation of megakaryocytes from their committed progenitor cells, and it regulates the production and circulation of platelets. TPO has also been reported to promote the apoptosis of hypoxia-sensitized neurons and to inhibit neuronal differentiation.

TNF-related apoptosis-inducing ligand (TRAIL), also known as Tumor Necrosis Factor Super-Family 10 (TNFSF10) or apoptosis 2 ligand (Apo2L), is a pleiotropic cytokine thatbelongs to the TNF superfamily. Full length TRAIL expressed in vivo is a type II transmembrane protein, although the soluble form also exists and functions. TRAIL has four major receptors: two death receptors DR4 and DR5, and two decoy receptors DcR1 and DcR2. TRAIL binds to the death receptors which recruits the FAS-associated death domain and activates caspases 8 and 10 which eventually leads to apoptosis. Because of its antitumor potential, TRAIL is activelystudied as a therapeutic agent. On the other hand, abnormal expression of TRAIL in small arteries can induce the proliferation of smooth muscle cells, thereby increasing vascular remodeling and pulmonary arterial hypertension.

TRAIL/Apo2L, also known as Tumor Necrosis Factor Super-Family 10 (TNFSF10), is a pleiotropic cytokine thatbelongs to the TNF superfamily. The full length TRAIL expressed in vivo is a Type II transmembrane protein, although the soluble form also exists and functions. TRAIL has four major receptors: two death receptors DR4 and DR5, two decoy receptors DcR1 and DcR2. TRAIL binds to the death receptors, recruits the FAS-associated death domain, activates caspases 8 and 10, and eventually leads to apoptosis. Because of its antitumor potential, TRAIL is actively studied as a therapeutic agent. On the other hand, abnormal expression of TRAIL in small arteries can induce the proliferation of smooth muscle cells, resulting in increasing vascular remodeling and pulmonary arterial hypertension.

Molecular Formula : C22H14D5Br4NO3

Molecular Formula : C16H19D6NO2 • HCl

Molecular Formula : C24 D3 H31 N2 O5

Molecular Formula : C24H29D5N2O5

Molecular Formula : C23 H32 N2 O5

Molecular Formula : C22H27D3N2O5• H2O

Molecular Formula : C22H25D5N2O5

Molecular Formula : C613C2H1515NO2

Molecular Formula : C6H6D6ClNO2

Molecular Formula : C18 H20 F N O3 S

Molecular Formula : C14 H11 Na O6 S

Molecular Formula : C31H32O14

Molecular Formula : C31H32O14

Molecular Formula : C26 H40 O5

Molecular Formula : C16H16

Molecular Formula : C24¹³CH36ClNO6

Molecular Formula : C20 H29 N . H Cl

Molecular Formula : C18H18O4

Molecular Formula : C9 D5 H9 O

Molecular Formula : C12 H24 N O5 S4

Molecular Formula : C10 H12 N2 O2

Molecular Formula : C16 H20 N2 O8

Molecular Formula : C16H20N2O8 .x(NH3)

Molecular Formula : C16 H19 N2 O8 . Na

Molecular Formula : C10 2H3 H9 N2 O2

Molecular Formula : C16H17D3N2O8

Molecular Formula : C5H5D4NO3

Molecular Formula : C14 H18 N6 O . 2HCl

Molecular Formula : C22H36N2O4 . C7H8O3S

Molecular Formula : C22 H24 F N3 O3

Molecular Formula : C38H58O4

Molecular Formula : C18H24D3NO3

Molecular Formula : C21 H36 O5

Molecular Formula : C24H32N4O7S

Molecular Formula : C22 D4 H21 Cl N2 O S . C10 H16 O4 S

Molecular Formula : C2613CH27D3ClNO6S

Molecular Formula : C22H19Br2NO3

Molecular Formula : C20 H28 N4 O