1mg

Molecular Formula : C9 D3 H18 N3 O . 2 H Cl

Molecular Formula : C9H17D6Cl2N3O

Molecular Formula : C51H67D7N6O10

Molecular Formula : C29 H42 N6 O3

Molecular Formula : C11H15N5O5

Molecular Formula : C11 D3 H12 N5 O5

Molecular Formula : C14H26D6Cl2N4O2

Molecular Formula : C11H17D6N3O2

Molecular Formula : C12H17N5O4

Molecular Formula : C21 H22 N10 O4

Molecular Formula : C21H19D3N10O4

Molecular Formula : 13C2 C18 H16 15N N5 O3

Molecular Formula : 13C2 C7 H9 15N N4 O3

Molecular Formula : C36H50ClN3O10S

Molecular Formula : C41 D5 H50 Cl N4 O12 S

Molecular Formula : C12 D7 H4 N5

Molecular Formula : C32H53N7O11

Molecular Formula : C11H17N3O4

Molecular Formula : C9H12D4N2O5

Molecular Formula : C813C6H21N15N2O2S

Molecular Formula : C8 D4 H6 N6 . C H4 O

Molecular Formula : C11 H13 N5 O5

Molecular Formula : C26 H37 N5 O2

Molecular Formula : C7 D2 H12 N2 O3

Neutrophil Activating Peptide 2 (NAP-2) is proteolytically processed carboxyl-terminal fragments of platelet basic protein (PBP) which is found in the alpha-granules of human platelets. NAP-2 is a member of the CXC chemokines. Similar to other ELR domain containing CXC chemokines such as IL-8 and the GRO proteins, NAP-2 has been shown to bind CXCR-2 and to chemoattract and activate neutrophils. Although CTAP-III, β-TG and PBP represent amino-terminal extended variants of NAP-2 and possess the same CXC chemokine domains, these proteins do not exhibit NAP-2 activity. Recently, it has been shown that the additional amino-terminal residues of CTAP-III masks the critical ELR receptor binding domain that is exposed on NAP-2 and may account for lack of NAP-2 activity.

Nectin-2, also known as CD112 (Cluster of Differentiation 226) and PVRL2 (Poliovirus receptor-related 2), is a human plasma membrane glycoprotein. This protein is a modulator of T-cell signaling and can be either a costimulator of T-cell function or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, it stimulates T-cell proliferation and cytokine production, including that of IL-2, IL-5, IL-10, IL-13, and IFNγ. It can also inhibit T-cell proliferation upon interaction with PVRIG. Nectin-2 also acts as a receptor for herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV).

Molecular Formula : C9H14D4N2O4

Molecular Formula : C8H13D3N2O4

Molecular Formula : C8H12D6N4O2

NGAL (Neutrophil gelatinase-associated lipocalin, also known as lipocalin-2) is a small protein found in renal tubules. And its expression is dramatically increased in ischemic or nephrotoxic injury. It has been implicated in a variety of processes including cell differentiation, proliferation, survival and morphogenesis. NGAL is expressed in variety of tumor types including breast, ovary and pancreatic carcinomas.

NGAL (Neutrophil gelatinase-associated lipocalin, also known as lipocalin-2) is a small protein found in renal tubules. And its expression is dramatically increased in ischemic or nephrotoxic injury. It has been implicated in a variety of processes including cell differentiation, proliferation, survival and morphogenesis. NGAL is expressed in variety of tumor types including breast, ovary and pancreatic carcinomas.

NGF Receptor, also known as Gp80-LNGFR, p75 ICD, CD271 and TNFRSF16, is a type I transmembrane protein belonging to the TNF receptor family. It is expressed by both neuronal and non-neuronal cells. Signaling through NGF Receptor has been shown to regulate gene expression, cell migration and death. A truncated NGF Receptor containing only the extracellular domain has been detected in plasma, amniotic fluid and urine, and acts as a potent NGF antagonist.

Noggin, also known as NOG, is a homodimeric glycoprotein that bindsto and modulates the activity of TGF-beta family ligands. It is expressed in condensing cartilage and immature chondrocytes. Noggin antagonizes bone morphogenetic protein (BMP) activities by blocking epitopes on BMPs needed for binding to their receptors. Noggin has been shown to be involved in many developmental processes, such as neural tube formation and joint formation. During development, Noggin diffuses through extracellular matrices and forms morphogenic gradients, regulating cellular responses dependent on the local concentration of the signaling molecule.

Neuron-Specific
Enolase (NSE) is recognized as a biomarker for small cell lung cancer. It is
secreted from neuroendocrine cells as well as neurogenic tumors. Its levels in
NSE-secreting neoplasms correlate with tumor mass and tumor metabolic activity.

Neuron-Specific Enolase (NSE) is recognized as a biomarker for small cell lung cancer. It is secreted from neuroendocrine cells as well as neurogenic tumors. Its levels in NSE-secreting neoplasms correlate with tumor mass and tumor metabolic activity.

Neurotrophin-4 (NT-4), also known as NT-5, is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. Human NT-4 shares 48 – 52% aa sequence identity with human β-NGF, BDNF, and NT-3. Neurotrophins have six conserved cysteine residues that are involved in the formation of three disulfide bonds. NT-4 is expressed highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. NT-4 binds and induces receptor dimerization and activation of TrkB. NT-4 can signal through TrkB receptors and promotes the survival of peripheral sensory sympathetic neurons.

BNP and NT-proBNP are separated from precursor molecule proBNP via proteolytic processing. The BNP and NT-proBNP level in blood are proportional to the severity of cardiac dysfunction. They can be used for diagnosis of congestive heart failure (CHF).

Molecular Formula : C8 H16 N2 O4

Molecular Formula : C31 H32 Cl F2 N O3

Molecular Formula : C14 H18 N2 O2 . C4 H4 O4

Molecular Formula : C43 H46 N10 O14

Molecular Formula : C31H34N2O3

Molecular Formula : C44H48F2N8O4

Molecular Formula : C44H44D4F2N8O4

Molecular Formula : C16 H17 N O2 S

Molecular Formula : C15H15D4BrN4O4S

Molecular Formula : C31 H30 N6 O6

Molecular Formula : C15H18N4O2