1mg

Herpes Virus Entry Mediator (HVEM) is a transmembrane protein that is the receptor for TNFSF14 (also known as LIGHT) and is therefore referred to asTNFRSF14. HVEM is expressed broadly on immune cells such as T cells, natural killer (NK) cells and monocytes. The interaction of 3 molecules of LIGHT with three molecules of HVEM forms a hexameric complex that leads to the recruitment and retention of effector cells and activates NK cells to produce large amounts of IFN-γ and GM-CSF. In addition to the canonical binding partner LIGHT, HVEM can also bind to the inhibitory signaling protein, B- and T- lymphocyte attenuator (BTLA), which suppresses immune responses. Therefore, the HVEM network plays an important role in regulating immunity and the behavior of lymphocytes.

Molecular Formula : C29H29N3O4

Molecular Formula : C213CH4N15NO2

Molecular Formula : C613CH6D2ClN15N2O4S2

Molecular Formula : C7 2H2 H6 Cl N3 O4 S2

Molecular Formula : C18 2H6 H15 N O3

Molecular Formula : C713CH6D2F3N3O4S2

Molecular Formula : C17H19NO6S

Molecular Formula : C23H24D3NO9

Molecular Formula : C8 2H5 H10 N5 O

Molecular Formula : C27 H29 N5 O7 S

Molecular Formula : C27 2H4 H25 N5 O7 S

Molecular Formula : C13H12D6ClNO2

Molecular Formula : C23 H20 F3 N5 O3 S2

Molecular Formula : C16 H12 N2 O6

Molecular Formula : C5 2H3 H4 N3 O3

Molecular Formula : C32 H39 N O3

Molecular Formula : C32H34D5NO3

Molecular Formula : C24H25D4FN2O4

Molecular Formula : C35 H40 Cl2 N8 O4

Molecular Formula : C35 D5 H33 Cl2 N8 O5

Molecular Formula : C35 D8 H30 Cl2 N8 O5

Molecular Formula : C13 H19 Cl N2 O3

Molecular Formula : C6 2H4 H5 N3 O4

Molecular Formula : C25H34Cl3N5O3

Molecular Formula : C37 H48 N6 O6 S2

Molecular Formula : C18 H25 N3 O3

Molecular Formula : C13 D4 H10 N2 O

Molecular Formula : C21 H25 N O

Molecular Formula : C12 2H9 H9 N2 O4 S

Molecular Formula : C16H13D7N4O4S

Molecular Formula : ¹³CH4¹⁵N2O2

Molecular Formula : C H4 15N N O2

Molecular Formula : C16H14F3N5O2

Molecular Formula : C11H11O4P

Molecular Formula : C14H15D7N2O4

Molecular Formula : C18H24ClN3O3

Molecular Formula : C18H25ClN3NaO4S

Molecular Formula : C18 2H4 H22 Cl N3 O . H2 O4 S

Molecular Formula : C31 H30 O12

Molecular Formula : C18H22D6N4O8

Molecular Formula : C26 H28 Cl N O3

Molecular Formula : C22 H26 Cl N7 O3 S

Molecular Formula : C12H15Cl2NO2

Molecular Formula : C27 D11 H29 O4

Molecular Formula : C3H5O7P . (3/2Ba)

Molecular Formula : C23 H32 N6 O4 S2

Molecular Formula : C23H32N6O4S2

Molecular Formula : C21 D8 H19 Cl N2 O2 . 2 Cl H

Molecular Formula : C15 H13 N5 O2