1mg

Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. On mature hematopoietic, monocytes/macrophages and eosinophils. Additionally, Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) can stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma, and adenocarcinoma cell lines.

Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. On mature hematopoietic, monocytes/macrophages and eosinophils. Additionally, Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) can stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma, and adenocarcinoma cell lines.

Glia maturation factor beta (GMFB) contains an ADF-H domain，which is a member of the actin-binding proteins ADF family, GMF subfamily. It is a nerve growth factor implicated in nervous system development, angiogenesis, and immune function. GMFB causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells. It is phosphorylated after phorbol ester stimulation and is crucial for the nervous system. GMFB overexpression in astrocytes results in the increase of BDNF production. GMFB expression is increased by exercise, thus BDNF is important for exercise-induction of BDNF.

This product is specific for Human CD28

This product is specific for Human CD3

Molecular Formula : C18N15N3O2

Molecular Formula : C24H18N4O

Molecular Formula : C33H37F2N7O4

Molecular Formula : C29H31N5O3.HCl.x(H2O)

Molecular Formula : C29 H48 O

Molecular Formula : C18H21D3N4O

Molecular Formula : C23 H32 O4

Molecular Formula : C1613CH14D3ClO6

Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO-α, KC, neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-α). Human GRO-α, GRO-β (MIP2α),and GRO-γ (MIP2β)are products of three distinct, nonallelichuman genes. GRO-β and GRO-γ share 90% and 86% amino acid sequence homology with GROα, respectively. All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. GRO expression is inducible by serum or PDGF and/or by a variety of inflammatory mediators, such as IL-1 and TNF, in monocytes, fibroblasts, melanocytes and epithelial cells. In certain tumor cell lines, GRO is expressed constitutively. Similar to other alpha chemokines, the three GRO proteins are potent neutrophil attractants and activators. Additionally, these chemokines are also active toward basophils.All three GROs can bind with high affinity to the IL-8 receptor type B.

Human GRO-α, GRO-β (MIP-2α), and GRO-γ (MIP-2β) are products of three distinct, nonallelichuman genes. GRO-β and GRO-γ share 90% and 86% amino acid sequence homology, respectively, with GROα. All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors.GRO expression is inducible by serum or PDGF and/or by a variety of inflammatory mediators, such as IL-1 and TNF, in monocytes, fibroblasts, melanocytes and epithelial cells. In certain tumor cell lines, GRO is expressed constitutively.Similar to other alpha chemokines, the three GRO proteins are potent neutrophil attractants and activators. In addition, these chemokines are also active toward basophils.

GRO-α/KC/CXCL1 coded by CXCL1 gene at chromosome 5 is approximately 63% identity to that of mouse MIP2. KC is also approximately 60% identical to the human GROs. Mouse KC is a potent neutrophil attractant and activator. The functional receptor for KC has been identified as CXCR2. Based on the pattern of KC expression in a number of inflammatory disease models, KC appears to have an important role in inflammation. KC was found to be involved in monocyte arrest on atherosclerotic endothelium and may also play a pathophysiological role in Alzheimer’s disease.

Molecular Formula : C23H21N7O

Molecular Formula : C25H17F2N5O3S

Molecular Formula : C28H28FN5O3

Molecular Formula : C24 H19 F4 N5 O

Molecular Formula : C31 H38 N6 O2

Molecular Formula : C19 H28 O11

Molecular Formula : C19H25D3O12

Molecular Formula : C13H18O7

Molecular Formula : C13H15D3O7

Molecular Formula : 13C C8 H9 Cl2 15N3 O

Molecular Formula : 13C C2 H7 N3 O2

Molecular Formula : 13C2 C H7 N3 O2

Molecular Formula : C3H5D4N3O3S

Molecular Formula : C313C2H5N415NO

Molecular Formula : C2¹³C3H5N4¹⁵NO

Molecular Formula : 13C C21 H41 15N2 N3 O7 Si2

Molecular Formula : C913CH12N315N2O7P

Molecular Formula : C16 H23 N5 O15 P2 . 2 Na

Molecular Formula : C913CH13N5O5 xH2O

Molecular Formula : C513C5H15N5O6

Molecular Formula : 13C C9 H13 15N2 N3 O5 . H2 O

Molecular Formula : C513C5H14N5O8P

Guanosine-3′,5′-cyclic-monophosphothioate Sp-Isomer Sodium Salt

Molecular Formula : C10H13D2N5O6

Molecular Formula : C2H7Cl¹⁵N4O

Molecular Formula : C4H8N8 • 2HCl

Molecular Formula : C10H14N6Na3O13P3

Molecular Formula : C18H41N7 .1.5(H2SO4)

Molecular Formula : C28H41N5O6S

Molecular Formula : C21 H18 F3 N O3 S2

Molecular Formula : C21 H17 F4 N O3 S2

Molecular Formula : C21 H17 F4 N O5 S2

Molecular Formula : C21 H17 F4 N O4 S2

Molecular Formula : C48H82O18