1mg

Molecular Formula : C8H13D3N2O4

Molecular Formula : C8H12D6N4O2

NGAL (Neutrophil gelatinase-associated lipocalin, also known as lipocalin-2) is a small protein found in renal tubules. And its expression is dramatically increased in ischemic or nephrotoxic injury. It has been implicated in a variety of processes including cell differentiation, proliferation, survival and morphogenesis. NGAL is expressed in variety of tumor types including breast, ovary and pancreatic carcinomas.

NGAL (Neutrophil gelatinase-associated lipocalin, also known as lipocalin-2) is a small protein found in renal tubules. And its expression is dramatically increased in ischemic or nephrotoxic injury. It has been implicated in a variety of processes including cell differentiation, proliferation, survival and morphogenesis. NGAL is expressed in variety of tumor types including breast, ovary and pancreatic carcinomas.

NGF Receptor, also known as Gp80-LNGFR, p75 ICD, CD271 and TNFRSF16, is a type I transmembrane protein belonging to the TNF receptor family. It is expressed by both neuronal and non-neuronal cells. Signaling through NGF Receptor has been shown to regulate gene expression, cell migration and death. A truncated NGF Receptor containing only the extracellular domain has been detected in plasma, amniotic fluid and urine, and acts as a potent NGF antagonist.

Noggin, also known as NOG, is a homodimeric glycoprotein that bindsto and modulates the activity of TGF-beta family ligands. It is expressed in condensing cartilage and immature chondrocytes. Noggin antagonizes bone morphogenetic protein (BMP) activities by blocking epitopes on BMPs needed for binding to their receptors. Noggin has been shown to be involved in many developmental processes, such as neural tube formation and joint formation. During development, Noggin diffuses through extracellular matrices and forms morphogenic gradients, regulating cellular responses dependent on the local concentration of the signaling molecule.

Neuron-Specific
Enolase (NSE) is recognized as a biomarker for small cell lung cancer. It is
secreted from neuroendocrine cells as well as neurogenic tumors. Its levels in
NSE-secreting neoplasms correlate with tumor mass and tumor metabolic activity.

Neuron-Specific Enolase (NSE) is recognized as a biomarker for small cell lung cancer. It is secreted from neuroendocrine cells as well as neurogenic tumors. Its levels in NSE-secreting neoplasms correlate with tumor mass and tumor metabolic activity.

Neurotrophin-4 (NT-4), also known as NT-5, is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. Human NT-4 shares 48 – 52% aa sequence identity with human β-NGF, BDNF, and NT-3. Neurotrophins have six conserved cysteine residues that are involved in the formation of three disulfide bonds. NT-4 is expressed highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. NT-4 binds and induces receptor dimerization and activation of TrkB. NT-4 can signal through TrkB receptors and promotes the survival of peripheral sensory sympathetic neurons.

BNP and NT-proBNP are separated from precursor molecule proBNP via proteolytic processing. The BNP and NT-proBNP level in blood are proportional to the severity of cardiac dysfunction. They can be used for diagnosis of congestive heart failure (CHF).

Molecular Formula : C8 H16 N2 O4

Molecular Formula : C31 H32 Cl F2 N O3

Molecular Formula : C35 H43 N7 O5

Molecular Formula : C14 H18 N2 O2 . C4 H4 O4

Molecular Formula : C43 H46 N10 O14

Molecular Formula : C31H34N2O3

Molecular Formula : C44H48F2N8O4

Molecular Formula : C44H44D4F2N8O4

Molecular Formula : C16 H17 N O2 S

Molecular Formula : C15H15D4BrN4O4S

Molecular Formula : C31 H30 N6 O6

Molecular Formula : C15H18N4O2

Molecular Formula : C17 D6 H14 N4 O3

Molecular Formula : C27 H29 F N4 O . Cl H

Molecular Formula : C52H81NO14

Molecular Formula : C21 H22 Cl F N4 O3

Molecular Formula : C18H10D4ClNO4

Molecular Formula : C15 H23 N O3

Molecular Formula : C21H31NO9 xNH3

Molecular Formula : C14H18D5NO3

Molecular Formula : C34 H28 N4 O4

Molecular Formula : C2813C6H28N4O4

Molecular Formula : C16 H18 O6

Molecular Formula : C19 H22 N2 O2

Molecular Formula : C21 H31 N O8

Molecular Formula : C15 2H6 H17 N O2

Molecular Formula : C16 H23 N O2

Molecular Formula : C18 D5 H14 Cl F3 N O3

Molecular Formula : C22H23NO6

Molecular Formula : 13C4H14NO2PS2

Molecular Formula : C14 H9 Cl5 O

Molecular Formula : C43H54N4O8

Molecular Formula : C7 D5 H7 N2 O2

Molecular Formula : C22H23D5N2O2

Oncostatin M (OSM) is a multifunctional cytokine, and belongs to Interleukin-6 (IL-6) subfamily, which also includes IL-11, leukemia inhibitory factor (LIF), ciliary neurotropic factor, cardiotrophin-1, and novel neurotropin-1. In vivo, OSM is secreted from activated T cells, monocytes, neutrophils, and endothelial cells. OSM is related to LIF, and shares a receptor with LIF in human. Human OSM can bind to gp130 and recruit OSM Receptor β or LIF Receptor β to form a ternary complex. OSM stimulates the growth of different types of cells, including megakaryocytes, fibroblasts, vascular endothelial cells, and T cells. OSM inhibits the proliferation of several cancer cell lines, such as solid tissue tumor cells, lung cancer cells, melanoma cells, and breast cancer cells.

Oncostatin M (OSM) is a multifunctional cytokine, and belongs to Interleukin-6 (IL-6) subfamily, including IL-11, leukemia inhibitory factor (LIF), ciliary neurotropic factor, cardiotrophin-1, and novel neurotropin-1. In vivo, OSM is secreted from activated T cells, monocytes, neutrophils, and endothelial cells. OSM is related to LIF, and share a receptor with LIF in human. Human OSM can bind to gp130 and recruit OSM Receptor β or LIF Receptor β to form a ternary complex. OSM stimulates the growth of different types of cells, including megakaryocytes, fibroblasts, vascular endothelial cells, and T cells. On the other hand, OSM inhibits the proliferation of several cancer cell lines, such as solid tissue tumor cells, lung cancer cells, melanoma cells, and breast cancer cells.