50g

Molecular Formula : C9 H10 Cl N2 O5 P S

Molecular Formula : C20 H12 N2 O7 S2 . 2 Na

Molecular Formula : C8 H12 N4

Molecular Formula : C2 H4 N4 O2

Molecular Formula : C14H14N3S .Cl

Molecular Formula : C10H12N2

Molecular Formula : C5H12ClNO2

Molecular Formula : C4H10ClNO2

Molecular Formula : C5 H10 O3

Molecular Formula : C13 H12 O3

B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. Mature human B7-1 consists of a 208 amino acid extracellular domain (ECD) with two immunoglobulin-like domains, a 21 amino acid transmembrane domain, and a 25 amino acid cytoplasmic domain. Both human and mouse B7-1 and B7-2 can bind to either human or mouse CD28 and sCTLA-4. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells.

BAFF Receptor (BAFF-R), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFF-R is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFF-R/BAFF signaling plays a critical role in B cell survival and maturation.

B-cell activating factor, also known as BAFF, TALL-1, TNAK, and zTNF4, is a member of theTNF ligand superfamily designated TNFSF13B. Produced by macrophages, dendritic cells, and T lymphocytes, BAFF promotes the survival of B cells and is essential for B cell maturation. BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA/TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/BR3/TNFRSF 13C). These receptors are type III transmembrane proteins lacking a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL(a proliferation-inducing ligand), BAFF R selectively binds BAFF. The BAFF R extracellular domain lacks the TNF receptor canonical cysteine-rich domain (CRD) and contains only a partial CRD with four cysteine residues. Human and mouse BAFF R share 56% aa sequence identity. BAFF R is highly expressed in spleen, lymph node and resting B cells. It is also expressed at lower levels in activated B cell, resting CD4+ T cells, thymus and peripheral blood leukocytes.

Molecular Formula : C23 H25 N2 . Cl

Molecular Formula : C22 H44 O2

Molecular Formula : C9H12O2

Molecular Formula : C8 H7 N

Molecular Formula : C6H8O4S

Molecular Formula : C6H5ClO2S

Molecular Formula : C27 H42 N O2 . Cl

Molecular Formula : C6H4N2O2

Molecular Formula : C14 H12 O2

Molecular Formula : C7 H5 N

Molecular Formula : C13H11N

Molecular Formula : C34H26N6Na2O6S2

Molecular Formula : C14 H10 O4

Molecular Formula : C9 H10 O2

Molecular Formula : C14 H12 O2

Molecular Formula : C8H7ClO2

Molecular Formula : C8 H7 N S

Molecular Formula : C7 H8 S

Benzyl Nicotinate

Molecular Formula : C16 H17 N2 O4 S . K

Molecular Formula : C14 H12 O3

Molecular Formula : C10H17NO

Berberine Sulfate

Molecular Formula : C42 H70 O35

Molecular Formula : C3 H7 O6 P . 2 Na

Betacellulin (BTC) is a member of the EGF family of growth factors that also includes EGF, TGF-α, Amphiregulin, HB-EGF, Epiregulin, Tomoregulin, Heregulin and Neuregulins. Mature human BTC protein exhibits 80% amino acidsimilarity with mouse BTC protein. BTC is expressed in most tissues including kidney, uterus, liver and pancreas. It is also present in body fluids, including serum, milk, and colostrum. It is synthesized primarily as a transmembrane precursor, which is then processed to a mature molecule by proteolytic events. BTC signals through the EGF receptor.

Betacellulin (BTC) is a member of the EGF family of growth factors that also includes EGF, TGF-α, Amphiregulin, HB-EGF, Epiregulin, Tomoregulin, Heregulin and Neuregulins. Mature human BTC protein exhibits 80% amino acidsimilarity with mouse BTC protein. BTC is expressed in most tissues including kidney, uterus, liver and pancreas. It is also present in body fluids, including serum, milk, and colostrum. It is synthesized primarily as a transmembrane precursor, which is then processed to a mature molecule by proteolytic events. BTC signals through the EGF receptor.

Betacellulin (BTC) is a member of the EGF family of growth factors that also includes EGF, TGF-α, Amphiregulin, HB-EGF, Epiregulin, Tomoregulin, Heregulin and Neuregulins. Mature human BTC protein exhibits 80% amino acidsimilarity with mouse BTC protein. BTC is expressed in most tissues including kidney, uterus, liver and pancreas. It is also present in body fluids, including serum, milk, and colostrum. It is synthesized primarily as a transmembrane precursor, which is then processed to a mature molecule by proteolytic events. BTC signals through the EGF receptor.

Molecular Formula : C5 H11 N O2

Molecular Formula : C22 H28 F O8 P . 2 Na

Molecular Formula : C20 H36 O4

Molecular Formula : C12 H14 O6

Molecular Formula : C14 H18 O6

Molecular Formula : C16H35O2P

Molecular Formula : C12H12N2O2S

Molecular Formula : C8H16Cl2O