50g

Ciliary neurotrophic factor (CNTF) is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. CNTF was initially identified as a trophic factor for embryonic chick ciliary parasympathetic neurons in culture. Furthermore, the protein is also a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. In addition, CNTF is useful for treatment of motor neuron disease and it could reduce food intake without causing hunger or stress. Recombinant murine CNTF containing 198 amino acids and it shares 82 % and 95 % a.a. sequence identity with human and rat CNTF.

Ciliary Neurotrophic Factor (CNTF) is a polypeptide hormone which acts within the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. CNTF is a potent survival factor for neurons and oligodendrocytes and may play a role in reducing tissue damage during increased inflammation. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, however this phenotype is not causally related to neurologic disease.

Molecular Formula : C12H22CoO14. xH2O

Molecular Formula : Co (S C N)2

Molecular Formula : C6H9NO.C4H6O2

Molecular Formula : 2 C2 H3 O2 . Cu . H2 O

Molecular Formula : Br2 Cu

Molecular Formula : C6H8O7 xCu

Molecular Formula : Cl Cu2 H3 O3

Molecular Formula : ClCu

Molecular Formula : C4H8O4 .Cu .H2O

Molecular Formula : 2(C2H3O2)- . (Cu)2+

Molecular Formula : Cu(NO3)2 • 2.5[H2O]

Molecular Formula : No Data Available

Molecular Formula : C36H70CuO4

Molecular Formula : C9 H6 O2

Molecular Formula : C10H6O4

Molecular Formula : 2 C4 H7 N3 O . Zn . 2 Cl

Molecular Formula : C4H8O

Cytotoxic T lymphocyte-associated molecule-4 (CTLA-4) is a cell surface molecule that is closely related to CD28, and a powerful negative regulator of T cell activation. Structurally, CTLA-4 is a member of the Ig superfamily, having a single extracellular V-like domain , homology with CD28; The overall sequence homology between CD28 and CTLA-4 is about 20%, but they share a 27% (murine) to 31% (human) identity at the amino acid level. Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA-4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.

CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) is also known as CD152, is an Inhibitory receptor acting as a major negative regulator of T-cell responses. CTLA-4 is a member of the immunoglobulin superfamily, which is expressed on the surface of T cells and transmits an inhibitory signal to T cells. CTLA-4 and CD28 are homologous receptors expressed by both CD4+ and CD8+ T cells, which mediate opposing functions in T-cell activation. Both receptors share a pair of ligands expressed on the surface of antigen-presenting cells (APCs). The affinity of CTLA-4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory co-receptor CD28.

Molecular Formula : C9 H12

Molecular Formula : C H2 N2

Molecular Formula : C3 H4 N2 O

Molecular Formula : C3H3NO2

Molecular Formula : C9H16O2

Molecular Formula : C7 H11 N O

Molecular Formula : C6H10O

Molecular Formula : C5 H8 O

Molecular Formula : C4H5ClO

Molecular Formula : C5H8O

Molecular Formula : C4H7Br

Molecular Formula : C8H14O2

Molecular Formula : C6 H10 N6

Molecular Formula : C8 H9 N O2

Molecular Formula : C18 H32 O16 . 5 H2 O

Molecular Formula : C12 H22 O11 . 2 H2 O

Molecular Formula : C6H14ClNO2

Molecular Formula : C5 H12 O5

Molecular Formula : C5 H10 O5

Molecular Formula : C6 H14 N4 O2

Molecular Formula : C6H12O6

Molecular Formula : C6 H13 O12 P2 . Na . H2 O

Molecular Formula : C12 H16 O7

Molecular Formula : C6H12O6

Molecular Formula : C12 H22 O11

Molecular Formula : C6 H18 O24 P6 . Na . H2 O

Molecular Formula : C5 H12 N2 O2 . Cl H

Molecular Formula : C9 H19 N O4

Molecular Formula : C5 H11 N O2 S