ABflo® 488 Rabbit anti-Dog CD4 mAb

$275.66

Weight 3 lbs
Dimensions 5 × 5 × 5 in
Brand

Size/Quantity

Product Size

Shipping Condition

Manufacturer Part No

SKU: Abclonal-A22687 Category:

Description

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.

Please Submit Your Inquiries Below
Name(Required)
This field is for validation purposes and should be left unchanged.

What Makes Us Unique?

The Adva Tech portfolio offers a comprehensive workflow for your manufacturing needs with wide range of services that includes on site Inventory Management, Procurement Management, and Manufacturing Capabilities such as custom pack and private labeling.

Every client in the life science reagents and chemicals industry has unique needs and deserve unique solutions.

By partnering with the Adva Tech team, you will be supported throughout the life cycle of your product. This collaboration results in building better products, increasing efficiencies, and reducing cost & waste.

Adva Tech team is committed to your success and ready to help your company meet and exceed expectations.

Learn More