Biotinylated Recombinant Human CTLA-4/CD152 Protein

$2,200.00

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-RP00505B Category:

Description

CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152, is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses.CTLA4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation – a phenomenon which is particularly notable in cancers. It acts as an “off” switch when bound to CD80 or CD86 on the surface of antigen-presenting cells.

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