Biotinylated Recombinant Human  TNFRSF10B/DR5/TRAIL-R2/CD262 Protein

$686.40

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-RP02085B Category:

Description

DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

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