Biotinylated Recombinant Human TNFSF5/CD40 Ligand/CD154 Trimer Protein (Primary Amine Labeling)

$1,540.00

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-RP00538B- 500 μg Category:

Description

CD40 ligand or CD40L, also called CD154,? is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells.

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