Description
Bis-Tris, Biologics Grade buffer from ANGUS Chemical Company is a 99.0% pure buffering agent widely used as a diagnostic reagent and in gel electrophoresis separations, cell culture and bioprocessing applications. BIS-TRIS is ideal for a variety of biological-based formulations and nucleic acid systems and is known to complex with various metals.
• High purity, 99.0%
• Produced under a single global quality system that includes ISO 9001:2015
• Proven safe use in commercial drug products
• Highly soluble in water
• Ideal for use as an alternative to cacodylate, maleic acid and citrate
Uses and Applications
• Purification of biological molecules (downstream processing)
• Raw materials for API/drug substance formulation
• Cell culture buffer
• Fractionation of hemoglobin
• Gel electrophoresis
• Diagnostic reagents
• Research and development buffer (R&D)
• Analytical chromatography
• Non-sterile excipient
Typical Properties*
Purity: 99.9%
Molecular weight: 209.24
Melting point: 100.0 – 104.0°C
pH (1.0M aqueous solution @25°C): 9.5 – 11.0
Working pH Range: 5.8 – 7.2
pKa @ 20°C: 6.35 – 6.65
*Values shown are typical properties and are not to be considered product specifications. Test methods available upon request.
Safety and Handling Info