Caspase-8 Rabbit pAb

$229.46

Weight 3 lbs
Dimensions 5 × 5 × 5 in
Brand

Size/Quantity

Product Size

Shipping Condition

Manufacturer Part No

SKU: Abclonal-A0215- 100 μL Category:

Description

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined.

Please Submit Your Inquiries Below
Name(Required)
This field is for validation purposes and should be left unchanged.

What Makes Us Unique?

Adva Tech Group, Inc. is a distributor of Life Science Reagents and Chemicals. Our customer base includes industries such as Advanced Technologies, Biologicals, Clinical, Controlled Environments and Cleanroom Solutions, Education, Environmental, Federal Government, Forensics, Food and Beverage, Industrial, Molecular Diagnostics, Petrochemical, Pharmaceuticals and Biotechnology, State and Local Government.

As a newly established supplier of chemicals and equipment, we offer a comprehensive supply of chemistry & laboratory equipment, designed to meet the rigorous demands of your research, experiments, and manufacturing needs. Our inventory offers everything from basic to advanced chemicals and equipment, ensuring that whether you are conducting complex chemical manufacturing or routine testing, you have access to top-quality chemistry & lab supplies.

Learn More