CD35/CR1 Rabbit pAb

$229.46

Weight 3 lbs
Dimensions 5 × 5 × 5 in
Brand

Size/Quantity

Product Size

Shipping Condition

Manufacturer Part No

SKU: Abclonal-A10059 Category:

Description

This gene is a member of the receptors of complement activation (RCA) family and is located in the ‘cluster RCA’ region of chromosome 1. The genome is polymorphic at this locus with allele-specific splice variants encoding different isoforms, based on the presence/absence of long homologous repeats (LHRs). The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in this gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus, sarcoidosis and Alzheimer’s disease. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria.

Please Submit Your Inquiries Below
Name(Required)
This field is for validation purposes and should be left unchanged.

What Makes Us Unique?

The Adva Tech portfolio offers a comprehensive workflow for your manufacturing needs with wide range of services that includes on site Inventory Management, Procurement Management, and Manufacturing Capabilities such as custom pack and private labeling.

Every client in the life science reagents and chemicals industry has unique needs and deserve unique solutions.

By partnering with the Adva Tech team, you will be supported throughout the life cycle of your product. This collaboration results in building better products, increasing efficiencies, and reducing cost & waste.

Adva Tech team is committed to your success and ready to help your company meet and exceed expectations.

Learn More