Description
Recombinant CHO-K1 cells stably overexpress mas-related G-protein coupled receptor member X2 (MRGPRX2). MRGPRX2 couples to both Gi and Gq alpha subunits in mast cells naturally, so that the PLC signaling can be triggered within the cells by agonist binding. This cell line is recommended for agonist screening and functional validations with calcium flux assay.