Description
A phosphonic acid antibiotic. Specifically inhibits 1-deoxy-D-xylulose 5-phosphate (DXP) reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. It suppresses gram-negative and gram-positive bacteria and inhibits the non-mevalonic pathway in plants and the malaria parasite Plasmodium falciparum.