Freund’s incomplete adjuvant

$70.18

Freund’s Incomplete Adjuvant is a commonly used immunological adjuvant that contains non-metabolizable oils (paraffin oil) and surfactant (Arlacel A). Components are thoroughly mixed in controlled proportions and autoclaved prior to being vialed.

Features of Freund’s Incomplete Adjuvant (FIA):

  • Also called Incomplete Freund’s Adjuvant (IFA).
  • FIA can be utilized to produce water-in-oil emulsions of antigens.
  • By forming a depot at the injection site and stimulating the production of antibody-producing plasma cells, FIA predominantly induces a Th2-biased response.
  • FIA is typically used for subsequent boost immunizations.
Weight 1.00 lbs
Dimensions 0.47 × 1.18 × 1.18 in
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Manufacturer Part No

SKU: MPB-0855829

Description

This product is a mixture of paraffin oil (90%) and Arlacel A (10%). Freund’s Incomplete Adjuvant has been widely used as a potent adjuvant in immunization protocols and vaccine development.

Freund’s Incomplete Adjuvant forms a stable emulsion with water and the antigen, allowing for slow release of the immunogen at the injection site. The slow release of antigen is thought to contribute to the high and long-lasting antibody response. This sustained exposure to the antigen promotes a robust and persistent immune response, resulting in a higher titer of antibodies against the immunogen.

Freund’s Incomplete Adjuvant is commonly used in conjunction with subsequent boosts to enhance antibody titer after the initial immunization with Freund’s Complete Adjuvant (SKU: 0855828 MP Biomedicals).

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