[KD Validated] APAF1 Rabbit mAb

$94.99

application (WB, ELISA) & cross reactivity (Human, Mouse)

Weight	1.00 lbs
Dimensions	5.00 × 5.00 × 5.00 in
Manufacturer	ABclonal Technology
Size/Quantity	1-EA
Product Size	20ul
Manufacturer Part No	A28249
Ship to Residential	NO

SKU: Abclonal-A28249-20ul

SKU: Abclonal-A28249-20ul Category: Antibodies Brand: ABclonal Technology

Description

Description

Size quantity : 1-EA
Description : This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.

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