[KD Validated] Bid Rabbit mAb

$283.36

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-A23234 Category:

Description

This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2, and thus regulate apoptosis. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found.

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