[KD Validated] CREBBP Rabbit mAb

$283.36

Weight 3 lbs
Dimensions 5 × 5 × 5 in
Brand

Size/Quantity

Product Size

Shipping Condition

Manufacturer Part No

SKU: Abclonal-A26780- 100 μL Category:

Description

This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms.

Please Submit Your Inquiries Below
Name(Required)
This field is for validation purposes and should be left unchanged.

What Makes Us Unique?

The Adva Tech portfolio offers a comprehensive workflow for your manufacturing needs with wide range of services that includes on site Inventory Management, Procurement Management, and Manufacturing Capabilities such as custom pack and private labeling.

Every client in the life science reagents and chemicals industry has unique needs and deserve unique solutions.

By partnering with the Adva Tech team, you will be supported throughout the life cycle of your product. This collaboration results in building better products, increasing efficiencies, and reducing cost & waste.

Adva Tech team is committed to your success and ready to help your company meet and exceed expectations.

Learn More