Description
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.


![[KD Validated] HDAC1 Rabbit pAb](https://advatechgroup.com/wp-content/uploads/xabclonal-logo-1.webp.pagespeed.ic.LySEJwhWOg.webp)