Description
Size quantity : 1-EA
Description : This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.


![[KD Validated] IGF1R Rabbit pAb](https://advatechgroup.com/wp-content/uploads/2025/11/Abclonal-logo-1.jpg.pagespeed.ce.fjRV9E7ljW.jpg)