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[KD Validated] IRAK4 Rabbit mAb

[KD Validated] IRAK4 Rabbit mAb

$283.36

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-A20839- 100 μL Category:

Description

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

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