[KO Validated] ANAPC5 Rabbit pAb

$103.04

application (WB, IHC-P, IP, ELISA) & cross reactivity (Human, Mouse, Rat)

Weight	1.00 lbs
Dimensions	5.00 × 5.00 × 5.00 in
Manufacturer	ABclonal Technology
Size/Quantity	1-EA
Product Size	20ul
Manufacturer Part No	A7109
Ship to Residential	NO

SKU: Abclonal-A7109-20ul

SKU: Abclonal-A7109-20ul Category: Antibodies Brand: ABclonal Technology

Description

Description

Size quantity : 1-EA
Description : This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.

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