[KO Validated] GRK2 Rabbit pAb

$98.56

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-A1662 Category:

Description

This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer’s disease.

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