[KO Validated] Integrin alpha 2 (ITGA2/CD49b) Rabbit mAb

$113.96

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-A19068- 20 μL Category:

Description

This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

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