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[KO Validated] IRF3 Rabbit mAb

[KO Validated] IRF3 Rabbit mAb

$296.24

Monoclonal Antibodies

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-A19717-100μL
SKU: Abclonal-A19717-100μL Category:

Description

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7.

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