[KO Validated] PNP Rabbit pAb

$283.36

Weight	3 lbs
Dimensions	5 × 5 × 5 in
Brand	ABclonal Technology
Size/Quantity	1-EA
Product Size	100 μL
Shipping Condition	Wet Ice
Manufacturer Part No	A19885

SKU: Abclonal-A19885 Category: Polyclonal Antibodies

Description

Description

This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.

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