Description
This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.


![[KO Validated] TDP2 Rabbit pAb](https://advatechgroup.com/wp-content/uploads/xabclonal-logo-1.webp.pagespeed.ic.LySEJwhWOg.webp)