[KO Validated] TMED10 Rabbit pAb

$283.36

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-A18090- 100 μL Category:

Description

This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex’s gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer’s disease. This gene has a pseudogene on chromosome 8.

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