Mycoplasma is a frequent contaminant of cell cultures. It is the smallest and the simplest prokaryotic organism without cell walls. Therefore, it can pass through 0.22 μm filters easily. Moreover, the common antibiotics which target the cell wall, such as penicillin or β-lactam antibiotics, are ineffective against mycoplasmas. Mycoplasma contamination can severely affect the state of cells, causing changes in gene expression and metabolic characteristics, decelerated cell growth, abnormal cell differentiation, and cell death. It also severely affects cellular functions.

MP Biomedicals Myco-Out Mycoplasma Removal Spray is a ready-to-use peptide surfactant, which can quickly, efficiently, and non-toxically eliminate mycoplasma from working surroundings such as benches, biosafety cabinets, laminar flow cabinets, cell incubators, pipettes, liquid nitrogen tanks, door handles, etc. It also has a broad-spectrum antimicrobial disinfection effect.

Features:

Easy to Use: Myco-Out Mycoplasma Removal Spray simplifies Mycoplasma removal with a user-friendly, ready-to-use spray, eliminating the need for tedious methods like fumigation and alcohol wiping.

Fast and Non-Toxic: The mycoplasma-specific peptide surfactant derived from Bacillus subtilis works in just 5 – 10 minutes without harming cells.

Highly Effective: Efficacy studies confirm its effectiveness in removing Mycoplasma from surfaces like laminar flow cabinets coated with Mycoplasma-positive HeLa cell culture.

Broad Antimicrobial Spectrum: It eliminates Mycoplasma and inactivates various microorganisms, including bacteria, viruses, and fungal spores.

Safe to Use: The product is safe for users and the environment.

Performance

Figure 1: Detection of mycoplasma ratio from 4 different cell lines before and after being treated with Myco-Out Mycoplasma Removal Spray.