Papillary renal cell carcinoma Rabbit pAb

$83.16

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-A18781- 20 μL Category:

Description

This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.

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