PDGF-BB, Human

$2,596.13

Platelet-Derived Growth Factor-BB (PDGF-BB) is one of five dimers (PDGF-AA, AB, BB, CC, and DD) formed by 4 different PDGF subunits. In vivo, PDGF-BB is mainly produced in heart and placenta, and predominantly expressed by osteoblasts, fibroblasts, smooth muscle cells, and glial cells. An inactive precursor of PDGF-BB is produced in the endoplasmic reticulum and then activated by a proprotein convertase after secretion. PDGF-BB functions in a paracrine manner and promotes organogenesis, human skeletal development, and wound healing. PDGF-BB also promotes angiogenesis, particularly in the presence of Fibroblast Growth Factor basic. Therefore, PDGF-BB and its related pathways are potential pharmacological targets.

Weight	1.00 lbs
Dimensions	5 × 5 × 5 in
Manufacturer	GenScript Nanjing Inc.
Size/Quantity	1-EA
Product Size	1mg
Shipping Condition	Ambient
Manufacturer Part No	Z02892-1

SKU: GSB-Z02892-1 Category: Proteins Brand: GenScript Biotech

Description

Description

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