Description
Use Thermo Scientific™ ProPac™ WCX-10 LC Columns to provide exceptionally high resolution for separations of proteins and their variants. Based on stationary phases composed of 10µm non-porous polymeric beads, ProPac columns resolve isoforms that differ by a single charged residue. A thin, hydrophilic layer grafted to the particle core eliminates unwanted secondary interactions. The cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.
Multiple Formats for Greater Flexibility
• ProPac WCX-10 column is a weak cation-exchanger with a carboxylate functional group
• Column sizes range from 2 mm I.D., for analytical work, up to 22 mm I.D. for semi-prep work
Superior Performance for Protein Analysis
• Ideal for characterization and quality control assessment of MAbs and other proteins
• Well-suited for characterization of related protein variants including deamidation and MAb lysine truncation variants
• Unequaled high-resolution separations
• Unmatched column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing
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