Recombinant Cynomolgus Beta-2-Microglobulin/B2M Protein

$1,056.00

Weight	3 lbs
Dimensions	5 × 5 × 5 in
Brand	ABclonal Technology
Size/Quantity	1-EA
Product Size	500 μg
Shipping Condition	Wet Ice
Manufacturer Part No	RP02639

SKU: Abclonal-RP02639 Category: Proteins

Description

Description

The genetic and functional analysis of β2-microglobulin (B2M), a component of the HLA class-I complex.Acquired homozygous loss of B2M that caused lack of cell-surface HLA Class I expression in the tumor and a matched patient-derived xenograft (PDX). Downregulation of B2M was also found in two additional PDXs established from ICI-resistant tumors.

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