Recombinant Cynomolgus LILRB4/ILT-3/CD85k Protein

$422.40

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-RP02649- 100 μg Category:

Description

LILRB4,also known as CD85k and LIR-5, ILT3,? is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.

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