Recombinant Human BACE-1/ASP2 Protein

$246.40

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-RP00165- 100 μg Category:

Description

Beta-site APP-cleaving enzyme 1 (BACE1) is an aspartic-acid protease important in the formation of myelin sheaths in peripheral nerve cells.BACE-1 is the peptidase predominantly responsible for cleavage of the amyloid precursor protein beta site in the brain to generate the amyloid beta peptide. Because the amyloid beta peptide is a major component of amyloid plaques, BACE-1 has been implicated in the onset and/or progression of Alzheimer’s disease. BACE-1 is expressed in a variety of human tissues,such brain, pancreatic tissue.

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