Recombinant Human Gamma-glutamyl hydrolase/GGH Protein

$88.00

Weight	3 lbs
Dimensions	5 × 5 × 5 in
Brand	ABclonal Technology
Size/Quantity	1-EA
Product Size	10 μg
Shipping Condition	Wet Ice
Manufacturer Part No	RP01957

SKU: Abclonal-RP01957 Category: Proteins

Description

Description

Gamma-glutamyl hydrolase/GGH regulates intracellular folates and antifolates such as methotrexate (MTX) for proper nucleotide biosynthesis and antifolate-induced cytotoxicity, respectively. GGH is a ubiquitously-expressed enzyme that regulates intracellular folate metabolism for cell proliferation, DNA synthesis, and repair. cytoplasmic GGH might play a relevant role in the development and progression of invasive breast cancer.

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