Recombinant Human Gamma-glutamyl hydrolase/GGH Protein

$352.00

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-RP01957- 100 μg Category:

Description

Gamma-glutamyl hydrolase/GGH regulates intracellular folates and antifolates such as methotrexate (MTX) for proper nucleotide biosynthesis and antifolate-induced cytotoxicity, respectively. GGH is a ubiquitously-expressed enzyme that regulates intracellular folate metabolism for cell proliferation, DNA synthesis, and repair. cytoplasmic GGH might play a relevant role in the development and progression of invasive breast cancer.

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