Recombinant Human IL-17RB Protein

$1,320.00

Weight	3 lbs
Dimensions	5 × 5 × 5 in
Brand	ABclonal Technology
Size/Quantity	1-EA
Product Size	500 μg
Shipping Condition	Wet Ice
Manufacturer Part No	RP02679

SKU: Abclonal-RP02679- 500 μg Category: Proteins

Description

Description

Among inflammatory mediators, a growing body of evidence emphasizes the contribution of the interleukin 17 (IL-17) cytokine family in malignant diseases. Besides IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. In mouse models, IL-17B signaling through IL-17RB directly promotes cancer cell survival, proliferation, and migration, and induces resistance to conventional chemotherapeutic agents.

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