Recombinant Human IL-1R2/CD121b Protein

$1,408.00

Weight	3 lbs
Dimensions	5 × 5 × 5 in
Brand	ABclonal Technology
Size/Quantity	1-EA
Product Size	1000 μg
Shipping Condition	Wet Ice
Manufacturer Part No	RP01028

SKU: Abclonal-RP01028 Category: Proteins

Description

Description

Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.

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