Recombinant Human LR3-IGF-1(E51R) Protein

$64.40

Recombinant Human LR3-IGF-1(E51R) Protein is produced by E. coli expression system. The target protein is expressed with sequence (Gly49-Ala118) of human IGF-1 (Accession #P05019) with the substitution of an Arg for Glu at position three and the addition of a thirteen aa N-terminal extension.

Weight	1.00 lbs
Dimensions	5.00 × 5.00 × 5.00 in
Manufacturer	ABclonal Technology
Size/Quantity	1-EA
Product Size	50UG
Manufacturer Part No	RP00825
Ship to Residential	NO

SKU: Abclonal-RP00825-50UG

SKU: Abclonal-RP00825-50UG Category: Antibodies Brand: ABclonal Technology

Description

Description

Size quantity : 1-EA
Description : Long R3 IGF-1 (LR3 IGF-1) is a synthetic analog of IGF-1 that is generated by modifying the AA sequence for mature human IGF-1. These modifications include the substitution of an Arg for Glu at position three of the mature IGF-1 sequence and the addition of a thirteen aa N-terminal extension, which is derived from methionyl porcine Growth Hormone. These aa changes generate a protein that is still capable of binding to IGF-1 and Insulin receptors, but shows considerably lower affinity binding to IGFBPs compared to wild-type IGF-1. As a result, LR3 IGF-1 has an increased half-life and displays increased biological potency compared to IGF-1.

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