Description
Orexin A/Hypocretin-1,Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggestedBy Similarit，Orexin-A，Binds to orexin receptors HCRTR1/OX1R and HCRTR2/OX2R with a high affinity .Stimulates food intake.Modulates pituitary luteinizing hormone secretion in an ovarian steroid-dependent manner.