Recombinant Human TNF-beta Protein

$352.00

Weight 3 lbs
Dimensions 5 × 5 × 5 in
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SKU: Abclonal-RP01884- 100 μg Category:

Description

Tumor Necrosis Factor β (TNF- β ) is a secreted protein belonging to the tumor necrosis factor family. TNF- βbinds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM in homotrimeric form, binds toTNFRSF3/LTBR in heterotrimeric form with LTB. TNF- β forms heterotrimers with lymphotoxin-beta, whichanchors TNF- β to the cell surface. TNF- β mediates the inflammatory, immunostimulatory, and antiviralresponse, involves in the formation of second lymphoid organs during development, has a role in apoptosis.TNF-β is produced by lymphocytes and cytotoxic for a variety of tumor cells in vitro and in vivo.

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